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Cover art for Dr. Mario 64

Dr. Mario 64: native ports & recompilations

Nintendo 64Nintendo GameCube2001by Nintendo IRD
WindowsWindows✓macOSmacOSLinuxLinux✓Web browserWeb browser
172 GitHub stars across ports

Dr. Mario 64 (Nintendo 64, 2001) has 2 native ports. The most popular is Dr. Mario 64 Recompilation with 153 GitHub stars. You can play it natively on Linux, Windows.

Native ports

Decompilation projects

Screenshots

About

The flu season has come about, and it's Dr. Mario's duty to use his Megavitamins to heal the people of the land. However, Wario, wanting to have the fame that Dr. Mario has, attempts to steal the Megavitamins, but to no avail. Afterwards, Mad Scienstein and Rudy the Clown (from Wario Land 3) steal the Megavitamins, and both Dr. Mario and Wario give chase.

Frequently asked questions

Can I play Dr. Mario 64 on PC, Mac or Linux?
Dr. Mario 64 Recompilation covers Windows and Dr. Mario 64 Recomp covers Linux. Nothing covers macOS yet. Windows builds may also run on macOS through CrossOver, which is not a native port.
What's the best way to play Dr. Mario 64 today?
Start with Dr. Mario 64 Recompilation, which runs on Windows. It's fully playable, and the latest release is v1.0.0. There's also Dr. Mario 64 Recomp.
Is Dr. Mario 64 Recompilation still being worked on?
It's slowed down. The last commit landed in December 2025. The latest release, v1.0.0, came out in December 2025.
Who's behind Dr. Mario 64 Recompilation?
Dr. Mario 64 Recompilation is made by Jason, AngheloAlf and sonicdcer.
Do I need the original game?
You need your own copy of Dr. Mario 64. Projects rebuild the game's code, not its art, audio or levels, so they read those from the copy you already own.
Is there a decompilation of Dr. Mario 64?
Dr. Mario 64 Decompilation is a decompilation of Dr. Mario 64. It turns the original machine code back into readable source, the groundwork most native ports are built on, but not something you play on its own.

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